Stem cells in retinal regeneration | 合法醫療器材資訊網

由CMRamsden著作·2013·被引用278次—Stemcelltherapyforretinaldiseaseisunderway,andseveralclinicaltrialsarecurrentlyrecruiting.Thesetrialsusehumanembryonic,foetaland ...

Stem cell therapy for retinal disease is under way, and several clinical trials are currently recruiting. These trials use human embryonic, foetal and umbilical cord tissue-derived stem cells and bone marrow-derived stem cells to treat visual disorders such as age-related macular degeneration, Stargardts disease and retinitis pigmentosa. Over a decade of analysing the developmental cues involved in retinal generation and stem cell biology, coupled with extensive surgical research, have yielded differing cellular approaches to tackle these retinopathies. Here, we review these various stem cell-based approaches for treating retinal diseases and discuss future directions and challenges for the field.

Keywords: A ge-related macular degeneration; Clinical trials; Retinitis pigmentosa; Stargardts disease; Stem cells.