Fluorescence in situ hybridization | 合法醫療器材資訊網

Fluorescenceinsituhybridization(FISH)isamolecularcytogenetictechniquethatusesfluorescentprobesthatbindtoonlythosepartsofanucleicacid ...

Genetic testing technique

Fluorescence in situ hybridization (FISH) is a molecular cytogenetic technique that uses fluorescent probes that bind to only particular parts of a nucleic acid sequence with a high degree of sequence complementarity. It was developed by biomedical researchers in the early 1980s[1] to detect and localize the presence or absence of specific DNA sequences on chromosomes. Fluorescence microscopy can be used to find out where the fluorescent probe is bound to the chromosomes. FISH is ofte...