VISCOSUPPLEMENTATION | 合法醫療器材資訊網

由MUdeRezende著作·2012·被引用19次—Highmolecularweightmoleculesofhyaluronicacidinterlinktoforma...“Highmolecularweight”,i.e.6x106Da:Synvisc®andSynvisc®One™.

With the aging of the worlds population, the prevalence of age-related diseases is continually increasing, especially osteoarthritis, the most common form of joint disease. In addition to its high prevalence, osteoarthritis has been correlated with high medical and social costs. Among the treatment methods, viscosupplementation (intra-articular injection of hyaluronic acid derivatives) has been gaining more prominence. The substances used are high molecular weight polysaccharides that, in addition to mechanical functions of weight distribution and joint lubrication, have anti-inflammatory properties and physical-chemical action on a variety of joint characteristics. These effects are directly proportional to the molecular weight and concentration of the drug used and any cross-links that may be present in the drug. Viscosupplementation is a sim...