Patent Foramen Ovale in Cryptogenic Ischemic ... | 合法醫療器材資訊網

High-RiskAnatomicalFeaturesofPFO·由SGIoannidis著作·2020·被引用3次—TheincidenceofPFOinthestrokepopulationtendstodecreasewithincreasingage(0–30years:34.3%,30–80 ...

The atrial septum is formed during the embryogenesis by two membranes growing from the atrial walls (septum primum and septum secundum), leaving an oval shaped fenestration (foramen ovale), which serves the right-to-left shunt (R-L shunt) of the fetal circulation (Figure 1[1]). The foramen ovale is sealed during the first year of life by the fusion of the two membranes. The failure of this process leads to an interatrial slit-like channel, the patent foramen ovale (PFO) (1–3) (Figure 1[2]). PFO is considered to be a subclass of ostium secundum defects (4). Other atrial septal defects include ostium primum defects, sinus venosus defects and coronary sinus defects. The size and morphology of the defect is individualized, depending on the structures which are involved (4).

Figure 1. (A) Normal atrial septum which results from the fusion of septum prim...