Alteplase | 合法醫療器材資訊網
Alteplase(t-PA)isathrombolyticmedication,usedtotreatacuteischemicstroke,acuteST-elevationmyocardialinfarctionpulmonaryembolismassociated ...
Thrombolytic medication
Alteplase, sold under the brand name Activase among others, is a biosynthetic form of human tissue-type plasminogen activator (t-PA). It is a thrombolytic medication used to treat acute ischemic stroke, acute ST-elevation myocardial infarction (a type of heart attack), pulmonary embolism associated with low blood pressure, and blocked central venous catheter.[5] It is given by injection into a vein or artery.[5] Alteplase is the same as the normal human plasminogen activator produced in vascular endothelial cells[6] and is synthesized via recombinant DNA technology in Chinese hamster ovary cells (CHO). Alteplase causes the breakdown of a clot by inducing fibrinolysis.[7]
It is on the World Health Organizations List of Essential Medicines.[8]
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