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由DXing著作·2016·被引用61次—Hyaluronicacid(HA)is,asanintegralcomponentofsynovialfluid,oftenusedinclinicalpracticefortreatingkneeOA.HAisregardedasa ...

According to the above mentioned methodology, the meta-analysis conducted by Bellamy et al.25 is with highest quality compared with others. The best available evidence hints that HA is an effective intervention in treating knee OA without increased risk of adverse events. Therefore, the current evidence supports the use of the HA in the treating knee OA.

Meta-analyses or systematic reviews are commonly regarded as the highest level of clinical evidence35. Clinicians can make meaningful clinical decisions with the help of meta-analyses or systematic reviews. However, a larger number of meta-analyses involving in the same clinical question have been published with conflicting results. This phenomenon was also occurred in the evidence-based study in HA injections for knee OA. Although numerous meta-analyses or systematic reviews have been written in treating knee OA via H...