RNase A | 合法醫療器材資訊網

2019年5月8日—Ribonucleases(RNases)arealargegroupofhydrolyticenzymesthatdegraderibonucleicacid(RNA)molecules.Thesearenucleasesthat ...

Ribonucleases (RNases) are a large group of hydrolytic enzymes that degrade ribonucleic acid (RNA) molecules. These are nucleases that catalyze the breakdown of RNA into smaller components. They are a superfamily of enzymes which catalyze the degradation of RNA, operating at the levels of transcription and translation.

The cytotoxic effects include RNA cleavage leading to the inhibition of protein synthesis and induction of apoptosis. These cytotoxic effects can be produced by applying RNase to the outside surface of the cell but it has been found that cytotoxicity increases 1000-fold when the enzyme is artificially introduced into the cytosol. ...