Glutaraldehyde | 合法醫療器材資訊網

由IMigneault著作·2004·被引用1610次—Nosinglemechanismseemstoberesponsibleforglutaraldehydecrosslinkingwithproteins.Allreportedformsofglutaraldehydeexhibitthe ...

Among the many available protein crosslinking agents, glutaraldehyde has undoubtedly found the widest application in various fields such as histochemistry (1–3[1]), microscopy (1,4,5), cytochemistry (6), leather tanning industry (7,8), enzyme technology (9–13[2]), chemical sterilization (14), and biomedical (15) and pharmaceutical sciences (16). Glutaraldehyde, a linear, 5-carbon dialdehyde, is a clear, colorless to pale straw-colored, pungent oily liquid that is soluble in all proportions in water and alcohol, as well as in organic solvents. It is mainly available as acidic aqueous solutions (pH 3.0–4.0), ranging in concentration from less than 2% to 70% (w/v). Glutaraldehyde has had great success because of its commercial availability and low cost in addition to its high reactivity. It reacts rapidly with amine groups at around neutral pH (17) and is more efficient than other ald...