[Diagnostic value of biochemical tumor markers in brain ... | 合法醫療器材資訊網

由GFlaschka著作·1990·被引用2次—[Diagnosticvalueofbiochemicaltumormarkersinbraintumors.Reviewoftheliteratureandownexperiencewithserumanalysisofsialicacid(NANA), ...

In a review of the literature the current knowledge of the diagnostic significance of sialic acid (NANA), neuron-specific enolase (NSE) and carcinoembryonic antigen (CEA) in the detection and differentiation of brain tumors is demonstrated. The efficiency of some additional biochemical tumor markers is briefly described. In a total of 101 patients of our own 63 patients operated on intracranial expansive lesions and 38 patients with non-tumoral diseases of the central nervous system were examined for their serum concentrations of NANA, NSE and CEA with additional determination of total serum protein (TSP) and C-reactive protein (CRP) concentrations. 24 benign, 15 semibenign, 12 semimalign and 12 malign expansions were compared with each other and with the controls for their tumor marker concentrations. The criteria of the diagnostic reliability (sensitivity, specificity, positive and negative predictive value) were calculated f...