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Cystatin C and Creatinine | 合法醫療器材資訊網

Cystatin C and Creatinine

Cystatin C and Creatinine

Why do labs need a marker in addition to creatinine to estimate glomerular filtration rate (GFR)?

A: Creatinine is a byproduct of muscle metabolism that is freely filtered by the kidney, the blood concentration of which reflects GFR. However, because muscle mass varies depending on age, sex, race, and level of fitness, the serum concentration of creatinine can still differ between individuals with the same level of kidney function.

The most recent equations for estimating GFR get around this issue to some extent by adjusting for age, sex, and race, which account for much of the inter-individual variability in muscle mass. The equations do not account for other factors that might be important, though, such as chronic illness, malnutrition, or even a larger-than-average muscle mass.

What are the advantages of cystatin C versus creatinine?

Cystatin C is made by al...

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Cystatin C and Creatinine | 合法醫療器材資訊網
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Creatinine versus cystatin C for renal function ... | 合法醫療器材資訊網
由 JZ Willey 著作 · 2020 · 被引用 4 次 — Estimated glomerular filtration rate (eGFR) is routinely utilized as a measure of renal function. While creatinine-based eGFR (eGFRcr) is widely used in clinical ... Read More
Creatinine | 合法醫療器材資訊網
由 SA Husain 著作 · 2018 · 被引用 11 次 — We compared chronic kidney disease (CKD) categorization using eGFRcr and cystatin C-based estimated GFR (eGFRcys) in an elderly, racially/ ... Read More
Clarifying the confusion of GFRs | 合法醫療器材資訊網
由 JG Toffaletti 著作 · 被引用 1 次 — Several reports also indicate that cystatin C is better than creatinine for predicting risk in cardiovascular disease [14], although other studies did not conclude that ... Read More
Creatinine versus cystatin C for renal function ... | 合法醫療器材資訊網
由 JZ Willey 著作 · 2020 · 被引用 4 次 — In an elderly, race/ethnically diverse cohort low eGFR is associated with risk of all​-cause mortality. Estimated GFR based on serum cystatin-C, ... Read More
Cystatin C vs creatinine as markers of renal function in ... | 合法醫療器材資訊網
由 P Hallberg 著作 · 2004 · 被引用 25 次 — Serum cystatin C has been suggested to be superior to creatinine for estimation of GFR, which may have relevance for the optimization of treatment with digoxin. Read More
Cystatin C is a more sensitive marker than creatinine for the ... | 合法醫療器材資訊網
由 M Mussap 著作 · 2002 · 被引用 445 次 — As GFR decreased from 120 to 20 mL/min/1.73 m2, cystatin C increased more significantly that serum creatinine, giving a stronger signal in comparison to that of ... Read More
Cystatin C predicts long term mortality better than creatinine in ... | 合法醫療器材資訊網
由 J Helmersson-Karlqvist 著作 · 2021 — The cystatin C equation increased C-statistics for death prediction (p < 0.001 vs. creatinine, p = 0.013 vs. combined equation). In conclusion ... Read More
Cystatin C versus Creatinine in Determining Risk Based on ... | 合法醫療器材資訊網
由 MG Shlipak 著作 · 2013 · 被引用 697 次 — The net reclassification improvement with the measurement of cystatin C, as compared with creatinine, was 0.23 (95% confidence interval [CI], ... Read More
The Difference Between Cystatin C– and Creatinine | 合法醫療器材資訊網
由 OA Potok 著作 · 2020 · 被引用 3 次 — from cystatin C versus creatinine level. Although clinicians ... eGFRcr-cys was calculated using the CKD-EPI creatinine–cystatin C equation. Read More
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