Yttrium 90 microspheres for the treatment of hepatocellular ... | 合法醫療器材資訊網

由KMemon著作·2013·被引用33次—Yttrium-90microspheresareradioactiveparticleswhichareincreasinglybeingemployedfortreatingpatientswithunresectablehepatocellularcarcinoma(HCC)​ ...

Yttrium-90 microspheres are radioactive particles which are increasingly being employed for treating patients with unresectable hepatocellular carcinoma (HCC). The procedure is called radioembolization. It involves the injection of micron-sized embolic particles loaded with a radioisotope by use of transarterial techniques. Because of the sensitivity of liver parenchyma and relative insensitivity of tumor, external radiation has played a limited role in treating HCC. (90)Y administered via arterial route directs the highly concentrated radiation to the tumor while healthy liver parenchyma is relatively spared due to its preferential blood supply from portal venous blood. This technique has proven useful for the majority of patients with HCC as most of them present in advanced stage, beyond potentially curative options (resection/liver transplantation). (90)Y microspheres can be used in downstaging large tumors to br...