Platelet function tests: a comparative review | 合法醫療器材資訊網

由RPaniccia著作·2015·被引用370次—Plateletaggregationisassessedbydetectingtheincreaseinelectricalimpedancegeneratedbytheaggregationofotherplateletsuponthose ...

Abstract

In physiological hemostasis a prompt recruitment of platelets on the vessel damage prevents the bleeding by the rapid formation of a platelet plug. Qualitative and/or quantitative platelet defects promote bleeding, whereas the high residual reactivity of platelets in patients on antiplatelet therapies moves forward thromboembolic complications. The biochemical mechanisms of the different phases of platelet activation – adhesion, shape change, release reaction, and aggregation – have been well delineated, whereas their complete translation into laboratory assays has not been so fulfilled. Laboratory tests of platelet function, such as bleeding time, light transmission platelet aggregation, lumiaggregometry, impedance aggregometry on whole blood, and platelet activation investigated by flow cytometry, are traditionally utilized for diagnosing hem...

Platelet aggregometry assay for evaluating the effects of ... | 合法醫療器材資訊網

Platelet Activation | 合法醫療器材資訊網

The investigator has several options when performing platelet assays by flow cytometry. Anticoagulant, blood collection, fixation, agonist, and gating/analysis ... Read More

Platelet Isolation and Activation Assays —BIO | 合法醫療器材資訊網

由 LC Burzynski 著作 · 2019 — Platelet activation drives the hemostatic response, and also ... Platelet activation assays: preparation of platelets for flow cytometry or lysate ... Read More

Luminometric Assay of Platelet Activation in 96 | 合法醫療器材資訊網

由 B Sun 著作 · 2001 · 被引用 34 次 — that platelet activation results in the release of ATP from dense granules, we report the development and optimization of a 96-well microplate luciferase assay to ... Read More

Measurement of platelet activation by fluorescence | 合法醫療器材資訊網

由 L Corash 著作 · 1990 · 被引用 150 次 — Platelet activation is postulated to play a critical role in the pathogenesis of thrombotic and hemorrhagic disorders. Previous assays for detection of activated ... Read More

Platelet function tests: a comparative review | 合法醫療器材資訊網

由 R Paniccia 著作 · 2015 · 被引用 370 次 — Platelet aggregation is assessed by detecting the increase in electrical impedance generated by the aggregation of other platelets upon those ... Read More

Detection of Platelet | 合法醫療器材資訊網

由 B Tardy 著作 · 2020 · 被引用 17 次 — Today, serotonin release assay (SRA), which measures the release of serotonin from dense granules when ... Read More

Platelet preparation for function testing in the laboratory and ... | 合法醫療器材資訊網

由 B Hechler 著作 · 2019 · 被引用 12 次 — In addition, the methodologies of the main platelet function tests (light transmission aggregation, flow‐based assays, and flow cytometric ... Read More

Platelet Aggregation Assay | 合法醫療器材資訊網

Platelet aggregation assays are the in vitro approaches most commonly used to assess platelet function and light transmission platelet aggregometry on ... Read More

A novel flow cytometry–based platelet aggregation assay ... | 合法醫療器材資訊網

2013年3月7日 — Several platelet function tests have been developed for use in the clinic and in experimental animal models. In particular, platelet aggregation is ... Read More

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