Industry Confusion | 合法醫療器材資訊網

2014年12月9日—PlacingHVPProcessedBiologicalIndicatorsinMedia.Ithasbeenmyexperiencethatthereisalotofconfusionpertainingtoa“6log ...

Placing HVP Processed Biological Indicators in Media

It has been my experience that there is a lot of confusion pertaining to a “6 log reduction” when it comes to assessing the microbiocidal mathematics associated with the decontamination of isolators.  In fact, a “6 log reduction” is not the same as “total kill“, and the purpose of this blog topic is to shed some light on this often misunderstood issue.

NOTE:  In the context of this discussion LOG10 will be used.

NOTE:  In the context of this discussion I use the term “total kill”.  Recently I have changed this terminology to “total inactivation” but the meaning is exactly the same.

First, let’s consider what a LOG equates to.  The LOG of number y with respec...