Relationship between everolimus blood concentration ... | 合法醫療器材資訊網
由LCoentrão著作·2010·被引用8次—Recently,Seradyn,Inc(In…...assessedusingtheInnofluorCerticanFluorescencePolarizationImmunoassayandthe...AhighdegreeofcorrelationbetweentheCMIAandFPIAmethods(r=0.90)wasconfirmedusingth
Everolimus, an immunosuppressive macrolide derivative of sirolimus, has a narrow therapeutic index and variable bioavailability. Assessment of blood concentration of everolimus is necessary to improve immunosuppressive efficacy without increasing potential adverse effects. Recently, Seradyn, Inc (Indianapolis, Indiana) introduced a fluorescence polarization immunoassay (Innofluor Certican Fluorescent Polarization Immunoassay [FPIA]) for quantitation of everolimus blood concentration. This immunoassay has concentration-dependent cross-reactivity with sirolimus, which must be considered in patients recently treated with that drug. In this short-term study, treatment in 53 renal transplant recipients was converted from a sirolimus-based regimen to an everolimus-based regimen. Patients were followed up for 3 months. We investigated whether cross-reactivity with everolimus also occurred with the Abbott Laboratories (Abbo...
Advances in Chromatographic Techniques for Therapeutic Drug ... | 合法醫療器材資訊網
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Relationship between everolimus blood concentration ... | 合法醫療器材資訊網
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【瑟若汀 英孚洛爾 卡巴馬平試驗系統】許可證字號:衛署醫器輸字第016517號
器材品名:瑟若汀英孚洛爾卡巴馬平試驗系統許可證字號:衛署醫器輸字第016517號註銷狀態:已註銷註銷日期:2014/06/12註銷理由:...