US20080194594A1 | 合法醫療器材資訊網
This application is a continuation-in-part of 10/964,236, filed Oct. 13, 2004, now pending, U.S. patent application Ser. No. 10/410,879, filed Apr. 9, 2003, now pending and PCT Application Serial No. PCT/US2004/011229, filed Apr. 9, 2004, the contents of which are incorporated by reference herein in their entirety.
BACKGROUND OF THE INVENTIONSAH hydrolase has been an attractive target for antiviral drug design based on the observation that many viruses require 5′-capped, methylated structures on their mRNA for efficient translation of viral proteins. Yuan et al., Exp. Opin. Ther. Patents, 9: 1197-1206 (1999); Yuan et al., in Adv. Antiviral Drug Des. vol 2, pp. 41-88, De Clercq (ed), JAI Press, Inc. London, UK (1996). Inhibition of SAH hydrolase results in inhibition of S-adenosyl-L-methionine (SAM)-dependent methylatio...
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器材品名:“聖原”水性潤滑凝膠(未滅菌)許可證字號:衛部醫器製壹字第005177號註銷狀態:註銷日期:註銷理由:有效日期:2019/04/01...