Seprafilm® adhesion barrier | 合法醫療器材資訊網

由MPDiamond著作·2012·被引用57次—Introduction.Seprafilmadhesionbarrierisabioresorbablemembranecomposedofchemicallymodifiedsodiumhyaluronate(HA)and ...

For over 15 years, Seprafilm’s effect on adhesion development has been evaluated in men, women, and children by multiple clinical investigators. The reported results of these studies have largely shown, often at repeat surgery, that Seprafilm is effective in reducing adhesion development or has led to another beneficial outcome. An overview of these published clinical reports is provided in Table .

The safety and efficacy of Seprafilm in abdominopelvic laparotomy were initially evaluated in two randomized controlled multicenter clinical trials. In one investigation, 183 patients with ulcerative colitis and familial polyposis undergoing colectomy with ileal pouch anal anastomosis and temporary loop ileostomy were enrolled [3]. The incidence, extent, and severity of adhesions to the underside of the abdominal wall incision were evaluated a...