Effects of polyglecaprone 25 | 合法醫療器材資訊網

由NYilmaz著作·2010·被引用43次—Effectsofpolyglecaprone25,silkandcatgutsuturematerialsonoralmucosawoundhealingindiabeticrats:anevaluationofnitricoxide ...

Objectives: The purpose of this study is to investigate the effects of monocryl (Polyglecaprone 25), silk and catgut suture materials on wound healing in diabetic rats and to evaluate NO (nitric oxide) dynamics.

Study design: Fourty-eight male Wistar-Albino rats weighing 220-270 g were used in this study. The rats were categorized into 2 groups, as control group (n=24) and streptozotocin (STZ) induced diabetic group (n=24). For each group, incision wounds were created on the inner cheek mucosa of the animals and wounds were closed primarily with three different types of sutures. These materials were sized 3-0 monocryl (polyglecaprone 25), silk and catgut sutures swaged on. Excisional biopsies were performed at 2nd, 7th, 14th and 21st day (2 rats per day) from the initial surgical procedure. Effects of these suture materials on wound healing and NOS (nitric oxide synthase) activities were compare...