Haemodynamic evaluation of pulmonary hypertension | 合法醫療器材資訊網

由DChemla著作·2002·被引用453次—Pulmonaryarterypressure.Cardiovasculartextbooksindicatea9–19mmHgrangefornormalmeanPAPatsealevel47,48.Inrestinghealthysubjectsaged6–45 ...

Pulmonary hypertension is characterised by the chronic elevation of pulmonary artery pressure (PAP) and pulmonary vascular resistance (PVR) leading to right ventricular enlargement and hypertrophy. Pulmonary hypertension may result from respiratory and cardiac diseases, the most severe forms occurring in thromboembolic and primary pulmonary hypertension.

Pulmonary hypertension is most often defined as a mean PAP >25 mmHg at rest or >30 mmHg during exercise, the pressure being measured invasively with a pulmonary artery catheter. Doppler echocardiography allows serial, noninvasive follow-up of PAPs and right heart function. When the adaptive mechanisms of right ventricular dilatation and hypertrophy cannot compensate for the haemodynamic burden, right heart failure occurs and is associated with poor prognosis.

The haemodynamic profile is the ma...