crystalloid versus blood cardioplegia – an experimental study | 合法醫療器材資訊網

由ABoening著作·2020—Generally,differentcardioplegiasolutionsareavailableforinducingcardiacarrest:crystalloid(CCP)orblood-based(BCP)solutions.

In our isolated rat heart experiments with an infarction model, we found that cold BCP was superior to cold CCP. Recovery of cardiac function after cardiac arrest was better after BCP, and the infarct size was smaller. Our results support the previous findings of Münch et al. who observed superior contractility after ischemia with BCP in a piglet model [18], Feng et al. who reported less apoptosis, preserved left ventricular function, and lower coronary resistance after BCP in a rabbit model [11], and Runge et al. who found more rapid normalization of myocardial metabolism in a porcine model [12]; all of these experiments were conducted without myocardial infarction. Julia et al. [13], Vinten-Johansen [14], and Catinella et al. [15] showed superiority of BCP over CCP, with better recovery of contractile function after BCP in dog heart infarction models. Only Coetzee et al. [16] showed superiority of CCP ...