CPK-MB | 合法醫療器材資訊網

由RKurapati著作·2021—ChronicskeletalmuscledisorderssuchasautoimmunemyopathiesandinflammatorymyopathycanresultinpersistentlyhighCK-MBlevelsinthe ...

Introduction

Creatine kinase (CK) is a dimeric enzyme that catalyzes the reversible phosphorylation of creatine by ATP.[1] In 1966 creatine kinase isoenzymes were identified in various tissues.[2] The isoenzymes of CK are dimers of either type B or type M polypeptide chains, BB isoenzymes are found in the central nervous system, and MM isoenzyme is a principal component in adult skeletal muscles.[3] The myocardium has 15% CK-MB isoenzyme and 85% CK-MM.[4] Skeletal muscles contain about 1% to 3% of CK-MB.[5]

Pathophysiology

Clearance of CK from Blood or Plasma

Creatine kinase (CK) and its isoenzymes are inactivated in the lymph by proteolysis.[6] Abnormal liver function or renal function does not affect the clearance of CK in a significant manner, and creatine kinase is not excreted in the urine.[7] Hypothyroidism retards the clearance of CK.[8]

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CK | 合法醫療器材資訊網

Extremely High CK | 合法醫療器材資訊網

由 SJ Tsai 著作 · 被引用 5 次 — His elevated CK-MB was most likely due to the presence of macro CK. It is important to be aware of different causes of CK isoenzyme elevation. Read More

False | 合法醫療器材資訊網

由 T Ota 著作 · 2020 — Abnormal serum levels of CK-BB are also often associated with neoplastic diseases. In lung cancer, increased serum CK-BB levels have been reported in cases of ... Read More

Creatine Kinase MB (Blood) | 合法醫療器材資訊網

Higher levels may also be caused by muscle damage elsewhere in your body, by diseases that affect your muscles, and by trauma to your chest. How is this test ... Read More

Several conditions causing elevation of serum CK | 合法醫療器材資訊網

由 SH Tsung 著作 · 1981 · 被引用 132 次 — The effects of various destructive processes on serum creatine kinase isoenzymes in 70 patients were studied. The MB isoenzyme was demonstrated in 17 of 70 ... Read More

Creatine Kinase | 合法醫療器材資訊網

2019年11月18日 — Because the major source of CK-MB is myocardium, an elevated CK-MB level reflects myocardial injury, including acute myocardial infarction, ... Read More

High Creatine Kinase (CK) | 合法醫療器材資訊網

由 N Maghamiour 著作 · 2014 · 被引用 29 次 — Elevated CK-MB fraction is seen in prostatic carcinoma and other underlying malignancy, such as breast cancer. Certain drugs that can increase ... Read More

Creatine Kinase | 合法醫療器材資訊網

由 CD Cabaniss 著作 · 1990 · 被引用 30 次 — A significant concentration of CK–MB isoenzyme is found almost exclusively in the myocardium, and the appearance of elevated CK–MB levels in serum is highly ... Read More

CPK-MB | 合法醫療器材資訊網

由 R Kurapati 著作 · 2021 — Chronic skeletal muscle disorders such as autoimmune myopathies and inflammatory myopathy can result in persistently high CK-MB levels in the ... Read More

Elevated Creatine Kinase - Symptoms | 合法醫療器材資訊網

Causes of elevated creatine kinase · Brain injury · Delirium tremens (severe alcohol withdrawal) · Muscle diseases such as dermatomyositis, polymyositis or ... Read More

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