Fractional Flow Reserve (FFR) Measurement | 合法醫療器材資訊網

Fractional flow reserve (FFR) measurement involves determining the ratio between the maximum achievable blood flow in a diseased coronary artery and the theoretical maximum flow in a normal coronary artery. An FFR of 1.0 is widely accepted as normal. An FFR lower than 0.75-0.80 is generally considered to be associated with myocardial ischemia (MI). [1]

FFR is easily measured during routine coronary angiography by using a pressure wire to calculate the ratio between coronary pressure distal to a coronary artery stenosis and aortic pressure under conditions of maximum myocardial hyperemia. [1] This ratio represents the potential decrease in coronary flow distal to the coronary stenosis. More recently, computed tomography (CT)-based FFR computations have been used to evaluate the functional severity of coronary artery stenoses, with FFRs derived from outflow boundary conditions based on conventional morphology generally agreeing with those based on pos...