OCT in Glaucoma Diagnosis | 合法醫療器材資訊網

由AYildiz著作·2018—Commonlyusedintheareaofophthalmologyespeciallyinthepast20years,theopticalcoherencetomography(OCT)hasprovidedsignificantcontributionsfor ...

Glaucoma is a progressive optic neuropathy where intraocular pressure is considered to be the most significant risk factor in its etiopathogenesis. The fundamental pathology of the disease is the progressive loss of the ganglion cells. Glaucoma predominantly affects the inner macular retinal layers: the macular RNFL (mRNFL), ganglion cell layer (GCL) and inner plexiform layer (IPL) where ganglion cell complex (GCC) consists of RNFL, GCL and IPL thickness [1]. The ganglion cell damage occurs at the lamina cribrosa level in the optic disc; first, the axons get damaged, then the ganglion cells which these axons are connected to disappear through a programmed cell death called apoptosis. This loss of axons and ganglion cells cannot be identified with any clinical diagnosis methods before it exceeds a certain critical threshold [2, 3, 4, 5]. Research ...