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由周弘傑著作·2014—高膽紅素血症；雙磷尿核苷-尿苷酸轉移1A1基因；母乳性黃疸；新生兒黃疸；活性氧；生理性體重下降；母嬰親善政策；Hyperbilirubinemia；uridine ...

Neonatal hyperbilirubinemia is a common problem with the incidence around 60~70%. The peak serum levels of unconjugated bilirubin in full-term Asian and American Indian neonates are almost double as those in Caucasian and black populations. The finding suggests that genetic factors are involved in the development of neonatal hyperbilirubinemia. Breastfeeding jaundice is common in exclusively breastfed neonates, but its pathogenesis is still unclear. The uridine diphosphate glucuronosyl transferase 1A1 (UGT1A1) gene polymorphism was shown to contribute to the development of neonatal hyperbilirubinemia. We hypothesize that the variation of UGT1A1 gene may contribute to neonatal breastfeeding jaundice. 211 G to A Variation of UDP-Glucuronosyl Transferase 1A1 Gene and Neonatal Breastfeeding Jaundice We prospectively enrolled 688 near term & term infants who were exclusively breast-fe...