從當前臨床上常見革蘭氏陰性桿菌及陽性球菌對Colistin及 ... | 合法醫療器材資訊網

由林雅筠著作·2013—AssessingtheEfficacyofColumbiaCNAAgarBasedontheCurrentColistinandNalidixicAcidSusceptibilitiesofClinicalGram-NegativeBacilliand ...

Columbia CNA agar with 5% sheep blood is a Gram-positive cocci selective medium. To make CNA inhibit Gram-negative clinical strains with high drug resistance without affecting the growth of Gram-positive cocci, this study analyzed the susceptibility of clinical Gram-negative bacilli and Gram-positive cocci to colistin and nalidixic acid, with the goal being to find the most appropriate antimicrobial content ratio. In this study, the method published by the Clinical and Laboratory Standards Institute(CLSI) was used to detect the minimum inhibitory concentration (MIC). To determine the MIC of two antimicrobials on various clinical isolates, 0.03-64 μg/mL nalidixic acid and 0.03-64 μg/mL colistin containing Mueller-Hinton (M-H) agar with blood were applied separately. The study tested 316 clinical strains from M-H agar and 60 Gram-negative strains grown on CNA to understand the patt...