Formulation and evaluation of controlled porosity osmotic ... | 合法醫療器材資訊網
由FSDasankoppa著作·2012·被引用27次—Formulationandevaluationofcontrolledporosityosmoticpumpfororaldeliveryofketorolac.JBasicClinPharm.2012Dec;4(1):2-9.doi: ...
Background: The osmotic drug delivery systems suitable for oral administration typically consist of a compressed tablet core that is coated with a semipermeable membrane that has an orifice drilled on it by means of a laser beam or mechanical drill. Ketorolac is a nonsteroidal agent with powerful analgesic. Oral bioavailability of ketorolac was reported to be 90% with very low hepatic first-pass elimination; the biological half-life of 4-6 hours requires frequent administration to maintain the therapeutic effect.
Aim: The aim of the current study was to design a controlled porosity osmotic pump (CPOP)based drug delivery system for controlled release of an NSAID agent, ketorolac tromethamine, which is expected to improve patient compliance due to reduced frequency; it also eliminates the need for complicated and expensive laser drilling and maintain continuous therapeutic concentration.
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(OROS) | 合法醫療器材資訊網
Development and optimization of buspirone oral osmotic ... | 合法醫療器材資訊網
Development of an oral push–pull osmotic pump of fenofibrate ... | 合法醫療器材資訊網
Formulation and evaluation of controlled porosity osmotic ... | 合法醫療器材資訊網
ORAL OSMOTIC DRUG DELIVERY SYSTEM | 合法醫療器材資訊網
Osmotic Drug Delivery System as a Part of Modified ... | 合法醫療器材資訊網
Osmotic Drug Delivery System as a Part of Modified ... | 合法醫療器材資訊網
Osmotic drug delivery system as a part of modified release ... | 合法醫療器材資訊網
Osmotic Pump | 合法醫療器材資訊網
Osmotic | 合法醫療器材資訊網
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