Juxtapid ® Lojuxta ® (lomitapide) | 合法醫療器材資訊網
Juxtapid®/Lojuxta...(lomitapide)...Unlikeothertherapies,lomitapidedoesnotworkbytryingtoclearthehighlevelsofcholesterol.Itworksbyreducing ...
Unlike other therapies, lomitapide does not work by trying to clear the high levels of cholesterol. It works by reducing the production and release of cholesterol from the liver and by reducing the absorption of cholesterol from the intestines following a meal. Specifically, lomitapide is an oral, selective inhibitor of microsomal triglyceride transfer protein (MTP) a protein necessary for the proper assembly and secretion of cholesterol containing molecules in the liver and the intestines. Inhibition of MTP reduces the levels of cholesterol containing molecules including cholesterol, LDL-C and triglycerides in the blood.
The U.S. Food & Drug Administration (FDA) granted authorisation for lomitapide under the trade name ‘Juxtapid’ in December 2012. Juxtapid® is indicated as:
An adjunct to a low-fat diet and other lipid-lowering treatments, includ...
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器材品名:SOM型人工骨頭許可證字號:衛署醫器輸字第000132號註銷狀態:已註銷註銷日期:2004/11/17註銷理由:未展延而逾期者...