Skin Substitutes for Treating Chronic Wounds | 合法醫療器材資訊網
![Skin Substitutes for Treating Chronic Wounds](https://i.imgur.com/6y29Lx7.jpg)
2018年11月27日—Naturalandsyntheticmaterial,suchascollagenandpolyglactin,respectively,maybeusedtocreatetheextracellularmatrixfortissue ...
![Skin Substitutes for Treating Chronic Wounds](https://i.imgur.com/6y29Lx7.jpg)
On July 24, 2019 and October 3, 2019 amendments were made to this protocol. To view the amendments, go to Summary of Protocol Amendments[1].
I. Background and Objectives for the Technical Brief Chronic WoundsWounds are disruptions of the skin’s structural and functional integrity. Wounds normally transition through four distinct phaseshemostasis, inflammation, cellular migration and proliferation, and remodelinguntil the wound structure and function are restored. Chronic wounds have failed to pass through the normal healing process in an orderly and timely manner and often remain in the inflammation phase. Patients with chronic wounds are burdened with loss of function, wound recurrence, and significant morbidity. Chronic wounds include pressure ulcers, diabetic foot ulcers, and venous leg ulcers. These wounds may need specific interventions to restart the healing process. Comple...
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