DOAC Use Increasing in Patients With Bioprosthetic Heart ... | 合法醫療器材資訊網

2021年3月8日—Theanalysisincludedpatientswhounderwentsurgicalaorticormitralvalvereplacementwitheithermechanicalorbioprostheticvalvesbetween ...

Due to a lack of randomized evidence, physicians should be cautious about using DOACs in this setting, Ankur Kalra says.

Patients undergoing surgical aortic or mitral valve replacement with bioprostheses in the United States are increasingly being prescribed direct oral anticoagulants (DOACs) at discharge, despite the lack of randomized evidence to support the practice and warnings against doing so, real-world data show.

Over a recent 3-year span, DOAC use at discharge increased from 3.30% to 6.64% in the aortic group and from 3.94% to 7.72% in the mitral group, Ankur Kalra, MD (Cleveland Clinic, OH), reported during the virtual CRT 2021 meeting.

DOAC prescriptions remained low at around 1% among patients who received mechanical heart valves, for whom there is a clear contraindication to use based on findings from the RE-ALIGN trial.[1]

“Until the completion of ...

Antithrombotic therapy for surgical prosthetic heart valves and ... | 合法醫療器材資訊網

由 WH Gaasch 著作 · 被引用 2 次 — Surgical replacement of a diseased heart valve with a prosthetic valve ... or NOACs) are contraindicated in patients with mechanical valves. Read More

Oral anticoagulants in atrial fibrillation with valvular heart ... | 合法醫療器材資訊網

由 AH Malik 著作 · 2019 · 被引用 13 次 — Similarly, there is a paucity of data regarding NOACs use in patients with a bioprosthetic heart valve (BPHV). We, therefore, performed a ... Read More

Non | 合法醫療器材資訊網

由 JG Andrade 著作 · 被引用 4 次 — The NOACs are contraindicated in atrial fibrillation patients … ... anticoagulants in atrial fibrillation patients with bioprosthetic valves. Read More

Nonvitamin K Antagonist Oral Anticoagulants Use in Patients ... | 合法醫療器材資訊網

由 V Russo 著作 · 2018 · 被引用 24 次 — ... (NOACs) in atrial fibrillation (AF) patients with bioprosthetic valves or prior surgical valve repair in clinical practice. Read More

NOAC non | 合法醫療器材資訊網

2020年11月15日 — Long-term anticoagulant therapy is required in patients with atrial fibrillation (AF) and a bioprosthetic mitral valve, but optimal strategy is ... Read More

NOAC? | 合法醫療器材資訊網

由 EY Sako 著作 · 2020 — the use of non-vitamin K oral anticoagulants (NOACs) as an alternative to vitamin K antagonists ... either a VKA or NOAC following bioprosthetic valve im-. Read More

DOAC Use Increasing in Patients With Bioprosthetic Heart ... | 合法醫療器材資訊網

2021年3月8日 — The analysis included patients who underwent surgical aortic or mitral valve replacement with either mechanical or bioprosthetic valves between ... Read More

Conversations in Cardiology | 合法醫療器材資訊網

2018年11月16日 — For mechanical valves, warfarin is indicated and NOACs are contraindicated ... of anticoagulation after all bioprosthetic valves (especially ... Read More

Non–Vitamin K Antagonist Oral Anticoagulants for Mechanical ... | 合法醫療器材資訊網

由 A Aimo 著作 · 2018 · 被引用 29 次 — The non–vitamin K antagonist oral anticoagulants (NOACs) are replacing vitamin K antagonists in many settings, including bioprostheses, because ... Read More

Anticoagulation for coexisting bioprosthetic aortic valve ... | 合法醫療器材資訊網

由 J Xu 著作 · 2020 — It is unknown if one NOAC is more effective than another in the prevention of bioprosthetic valve thrombosis. The patient in the case had ... Read More

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