Pentoxifylline Ameliorates Mechanical Hyperalgesia in a Rat ... | 合法醫療器材資訊網
由HKKim著作·2016·被引用22次—Pentoxifyllinealleviatedchemotherapy-inducedneuropathicpaininratsby...1DepartmentofPainMedicine,DivisionofAnesthesiaandCriticalCare, ...
Background: Chemotherapy-induced neuropathic pain is difficult to treat. Pentoxifylline inhibits the production of inflammatory cytokines including tumor necrosis factor α(TNF- α) and interleukin 1β (IL-1β).
Objective: The aims of our study were to investigate the analgesic and preventive effects of pentoxifylline on paclitaxel-induced neuropathic pain in rats and to identify its mechanisms of action.
Study design: Controlled animal study.
Methods: Neuropathic pain was induced with intraperitoneally injected paclitaxel on 4 alternate days in male Sprague-Dawley rats. Pentoxifylline was administered systemically as a single injection and a continuous infusion before or after the injection of paclitaxel. The mechanical threshold for allodynia was measured by using von Frey filaments. Protein levels and localization of inflammatory cytokines were performed by using Wes...
Management of Periprocedural Anticoagulation (Neuraxial ... | 合法醫療器材資訊網
Guidelines For The Use Of Antithrombotic Agents In The ... | 合法醫療器材資訊網
Neuraxial Anesthesia and Peripheral Nerve Blocks in Patients ... | 合法醫療器材資訊網
Anticoagulant and Antiplatelet Management for Spinal ... | 合法醫療器材資訊網
Quality Institute | 合法醫療器材資訊網
SPINE SECTION Anticoagulant and Antiplatelet Management ... | 合法醫療器材資訊網
(PDF) Acute paraplegia due to epidural hematoma in an ... | 合法醫療器材資訊網
The Synergistic Effects of Pentoxifylline on Systemic and Re ... | 合法醫療器材資訊網
Pentoxifylline Ameliorates Mechanical Hyperalgesia in a Rat ... | 合法醫療器材資訊網
Pentoxifylline Inhibits Epidural Fibrosis in Post | 合法醫療器材資訊網
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