Serum CA125 concentration as a predictor of ... | 合法醫療器材資訊網

由CJHuang著作·2016·被引用30次—CA125concentrationhasbeenstudiedrarelyinmales.ThisstudyshowsthatitsconcentrationmayalsoincreaseinmenwithPD.Itisintriguingthatthetumor ...

Peritoneal dissemination (PD) is one of the most troublesome metastases of colorectal cancer (CRC) and has a significant impact on the prognosis.[1] Imaging procedures, mainly computed tomography (CT), have insufficient sensitivity to help in the diagnosis of small PD lesions,[2] and PD is usually not diagnosed without an operation.

First reported by Bast et al in 1981, carbohydrate antigen 125 (CA125) is a sensitive tumor marker for ovarian cancer.[3] CA125 is found in mesothelial cells of the peritoneum, pleura, pericardium, epithelium of the fallopian tubes, endometrium, and endocervix.[4] Irritation of these foci in certain reactive or neoplastic lesions causes the serum CA125 concentration to increase. CA125 can also be detected in the tissue of gastrointestinal cancers, including stomach and colon cancer.[5] Previous reports have shown that CA12...