Burkholderia cepacia complex infections | 合法醫療器材資訊網

由MMSfeir著作·2018·被引用31次—Burkholderiacepaciacomplex(Bcc)isanemergingpathogencauseslife-threateninginfectionsincysticfibrosispatients.

Burkholderia cepacia complex (Bcc) is an emerging pathogen causes life-threatening infections in cystic fibrosis patients. This narrative review aims to highlight an update on the epidemiology, the microbiological diagnostic methods, the antimicrobial resistance mechanisms, and the most current as well the promising therapeutic options for Bcc. Although Bcc plays a role in crop growth due to its fungicidal activity and pesticide metabolizer, it has been frequently implicated in outbreaks in the United States and Worldwide due to contaminated medicines or medical devices. Phenotypic methods of microbial identification often lack sensitivity. Consequently, the diagnosis is mainly based on molecular testing which is critical for species identification. Disc diffusion is a poorly reproducible method for antibiotic susceptibility testing of Bcc when compared to broth microdilution, agar dilution or Etest. Bcc is naturall...