Endothelial Dysfunction | 合法醫療器材資訊網

Endothelialdysfunctioncanbedefinedasreducedbio-availabilityofNitricOxide(NO)...assessmentthatearnedFDAapprovalofEndoPATtestingin2003.

The problem with this method is that this technique is very invasive and requires hospitalization. It’s very expansive and it’s not justified for healthy or asymptomatic patients. In 1992 scientists developed a research technique for assessing endothelial dysfunction using high resolution US imaging of the brachial artery. This technique (also called a reactive hyperemia procedure) requires 5 min occlusion and release of the brachial artery blood flow using a blood pressure cuff, and manually measuring the diameter of the brachial artery using a high-frequency ultrasound imaging probe. If the brachial artery diameter increases in less than 5% it indicates endothelial dysfunction and a sign of cardiovascular disease. However, if the brachial artery diameter increases more than 10% it is a clear indication for healthy endothelial function. The healthier the artery – the larger the reactive hyperemic response....