Effects of Scleral Contact Lenses for Keratoconus ... | 合法醫療器材資訊網

由MFormisano著作·2021—Conclusion:ScleralCLsremarkablyimprovedvisualacuityinkeratoconuspatientswhencomparedtoglassesorRGPcontactlenses.Evenifitwas ...

Keratoconus is a non-inflammatory corneal disease that causes a gradual and progressive corneal ectasia. The disease typically involves both eyes.1 In keratoconus, all cornea layers, particularly the stroma, are characterized by a disruption in the arrangement of collagen fibrils, alterations in proteoglycans expression, and unstable interconnectivity of collagen lamellae, with varying degrees of severity.2 Changes in stromal biomechanics result in paracentral steepening of the cornea, apical thinning, and conic shaping of the cornea.3 The displaced optic zone leads to irregular astigmatism, significant coma aberration, and a remarkable reduction in the quality of vision.4

Traditional sphero-cylindrical spectacles do not provide significant visual improvement in keratoconus patients, due to higher-order aberrations (HOAs) typical of the keratoconic cornea. Consequently, wh...