Conditioned pain modulation | 合法醫療器材資訊網

ConditionedPainModulation,alsoknownasCPMorDNIC,isaphenomenonofcentralnervoussystemdescendinginhibitionwhichcanbetestedusing ...

The human central nervous system has the ability to modulate pain sensation through processes of inhibition and excitation, by directional “top-down” (from cortical and sub-cortical areas / brainstem to spinal cord) or “bottom-up” (from the periphery to the spinal cord to the brain) mechanisms.

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Endogenous pain inhibition often refers to central pain inhibition by the body. Conditioned Pain Modulation (CPM) is a term to describe one of the psychophysical paradigms in which central pain inhibition is tested by means of “pain inhibits pain”. The parallel phenomenon for CPM in animal models is called Diffuse Noxious Inhibitory Controls (DNIC).

Significance of conditioned pain modulation capacity