Hyaluronidase Use During Pregnancy | 合法醫療器材資訊網

2021年6月4日—HyaluronidaseBreastfeedingWarnings...Cautionisrecommended....Comments:-Considerthedevelopmentalandhealthbenefitsof ...

Brand names: Amphadase[1], Hydase[2], Hylenex[3], Vitrase[4], Wydase

Medically reviewed[5] by Drugs.com. Last updated on Sep 20, 2023.

Animal studies have at subcutaneous doses up to 2,200,00 U/kg of recombinant human hyaluronidase no evidence of teratogenicity, but did show increased fetal resorptions and reduced fetal weight; the no effect daily dose was 360,000 U/kg (suggested human dose: 0.8 U/kg in a 60 kg subject); subcutaneous doses up to 1,100,000 U/kg showed no effects on sexual maturation, learning or memory of offspring, or ability of offspring to reproduce. There are no controlled data in human pregnancy.

AU Exempt: Medications exempted from pregnancy classification are not absolutely safe for use in pregnancy in all circumstances. Some exempted medicines, for ...