Bovine pericardium used as a cardiovascular patch | 合法醫療器材資訊網

由ACPires著作·1999·被引用25次—Thefateofimplantedglutaraldehyde-preservedbovinepericardialpatchesincardiovascularapplicationsdependsonthreefactors:1)thecontactsurface,2)the ...

Background: The use of glutaraldehyde preserved bovine pericardium in valvular prostheses is well known. Although widely used clinically as patch material, bovine pericardium has not been extensively studied in this setting.

Methods: With this objective, 21 dogs received a standard bovine pericardial patch to partially replace the aortic, left atrial, or pericardial walls. The dogs were randomly divided into three groups according to implant duration. Group 1 consisted of 6 dogs evaluated surgically after 33 to 43 postoperative days, Group 2 with 7 dogs reoperated after 120 to 165 days, and Group 3 with 8 dogs reoperated after 225 to 305 days.

Results: Microscopic and macroscopic evaluation demonstrated: 1) the wrinkled surface of the bovine pericardium adhered to neighboring structures whereas the smooth surface did not adhere to the epicardium; 2) the bovine pericardial patch did ...