How to Interpret Elevated Cardiac Troponin Levels | 合法醫療器材資訊網

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Cardiac troponin (cTn) testing is an essential component of the diagnostic workup and management of acute coronary syndromes (ACS). Although over the past 15 years the diagnostic performance of the previous gold-standard assay, creatine kinase-MB, has not changed appreciably, the ever-increasing sensitivity of cTn assays has had a dramatic impact on the use of cTn testing to diagnose ACS.1 Here, we present 3 recent clinical cases from the emergency department with acute chest discomfort that exemplify the challenges introduced by high-sensitivity cTn assays: a 48-year-old man who presented to the emergency department with chest discomfort lasting 2 hours and a 3-day history of flu-like symptoms whose ECG showed diffuse ST-segment changes, a 60-year-old woman with a medical history of heart failure who presented to the emergency department with chest pain lasting 1.5 hours whose ECG was nondiagnostic, and a 54-year-o...