10 | 合法醫療器材資訊網

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Chemical compound

10-Methacryloyloxydecyl dihydrogen phosphate (10-MDP, MDP Monomer) is used for dental adhesive materials. The phosphate monomer was developed by Kuraray co., Ltd. with focus on the dental adhesion technology in 1981.[1]

MDP is synthesized according to the following reaction. At first, 10-hydroxydecy methacrylate is synthesized by reaction with methacrylic acid and 1,10-decandiol. Next, phosphoryl chloride is added to 10-hydroxydecy methacrylate, then, the bonding of P-Cl is hydrolyzed.[2]

In the late 1970s, tooth adhesion phosphate monomer: 2-methacryloyloxethyl phenyl hydrogen phosphate (Phenyl-P) was developed for tooth substance saving restoration technique.[3] 4-Met...