Creatine Kinase | 合法醫療器材資訊網

由CDCabaniss著作·1990·被引用27次—Creatinekinase(CK),formerlyknownascreatinephosphokinase,isanintracellularenzymepresentingreatestamountsinskeletalmuscle,myocardium,and ...

Creatine kinase (CK), formerly known as creatine phosphokinase, is an intracellular enzyme present in greatest amounts in skeletal muscle, myocardium, and brain; smaller amounts occur in other visceral tissues.

Disruption of cell membranes due to hypoxia or other injury releases CK from the cellular cytosol into the systemic circulation. On this basis, elevated serum levels of CK have been used as a sensitive but nonspecific test for myocardial infarction. The poor specificity reflects the ubiquity of CK in many tissues other than the myocardium.

Because of the many current assay methods in use, there is no standard reference value for serum CK. Normal values are best determined locally based on the method employed and the ranges for healthy controls. Values are expressed in international units per liter.

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