癌症微創介入治療中心 | 合法醫療器材資訊網

Irreversibleelectroporation(IRE),alsoknownasnanoknifetreatment,isaminimallyinvasiveablationmethod,whichdestroystumorsusingintenseburstsof ...

Principle Irreversible electroporation (IRE), also known as "nanoknife" treatment, is a minimally invasive ablation method, which destroys tumors using intense bursts of electricity through two- to six-needle electrodes operating in pairs. The electricity causes nano-sized perforations on the membrane of tumor cells, causing a loss of homeostasis. The cells undergo apoptosis and the affected area immediately becomes necrotic. The current flow field is limited by the position and distance between positive and negative electrodes as well as the voltage strength; therefore, the ablation zone remains relatively consistent as long as the treatment conditions remain unchanged. This means that the region peripheral to the ablation zone is largely unaffected and the margin between the two regions is well-defined. Thermal therapy and cryotherapy are unable to achieve this level of specificity. IRE provides unprecedented ...