Activated clotting time versus activated partial thromboplastin ... | 合法醫療器材資訊網

由RJSimko著作·1995·被引用39次—TheaPTTisusedmorefrequentlyforroutinemonitoring;theACTisusedinspecializedsituationsrequiringlargeheparindoses.TheACTistypicallyperformedat ...

Objective: To compare and contrast the activated partial thromboplastin time (aPTT) and the activated clotting time (ACT) for the therapeutic monitoring of heparin therapy.

Data sources: Relevant articles were identified through an English-language MEDLINE search from 1966 to 1995. Additional sources were identified from the reference lists of these articles.

Study selection: Studies that investigated the use and limitations of the individual assays and those offering direct comparisons were chosen for review.

Data extraction: Features demonstrating clinical applications and limitations of the aPTT and the ACT were extracted. Where possible, data suggesting preferential application of either assay also were extracted.

Data synthesis: Both the aPTT and ACT are clinically useful for the monitoring of heparin therapy. The aPTT is used more frequently for r...