Comparison of corneal endothelial cell images from a ... | 合法醫療器材資訊網

由ASKitzmann著作·2005·被引用69次—Purpose:Wecomparedendothelialcelldensity(ECD)fromimagesrecordedbytheConfoScan3confocalmicroscopeandanoncontactspecularmicroscope.

Purpose: We compared endothelial cell density (ECD) from images recorded by the ConfoScan 3 confocal microscope and a noncontact specular microscope.

Methods: Endothelial micrographs of 50 normal corneas of 25 subjects were acquired by a Konan Noncon Robo noncontact specular microscope (Konan Medical, Inc., Hyogo, Japan) and a ConfoScan 3 confocal microscope (Nidek Technologies, Inc, Greensboro, NC). ECD was determined in images from both instruments by using the HAI CAS System Corners Method (HAI Labs, Inc., Lexington, MA). Distances in the images from both machines were calibrated from images of an external scale. Images from the ConfoScan 3 were also assessed using the automated endothelial analysis software provided by the manufacturer, with and without manual correction.

Results: The ECD was 2634 +/- 186 cells/mm(2) (mean +/- SD) and 2664 +/- 173 cells/mm(2) by the Robo and...