PHOTODYNAMIC THERAPY OF CANCER | 合法醫療器材資訊網

由PAgostinis著作·2011·被引用3590次—Photodynamictherapy(PDT)isaclinicallyapproved,minimallyinvasivetherapeuticprocedurethatcanexertaselectivecytotoxicactivity ...

Despite progress in basic research that has given us a better understanding of tumor biology and led to design of new generations of targeted drugs, recent large clinical trials for cancer, with some notable exceptions, have been able to detect only small differences in treatment outcomes.1-2 Moreover, the number of new clinically approved drugs is disappointingly low.3 These sobering facts indicate that to make further progress it is necessary to put an emphasis on other existing but still underappreciated therapeutic approaches. Photodynamic therapy (PDT) has the potential to meet many currently unmet medical needs. Although still emerging, it is already a successful and clinically approved therapeutic modality used for the management of neoplastic and non-malignant diseases. PDT was the first drug-device combination approved by the FDA almost two decades ago, but even so remains underutilized clinically.

PDT consists of three essential components - photosens...