Ethylene Oxide Sterilization | 合法醫療器材資訊網

ThebasicETOsterilizationcycleconsistsoffivestages(i.e.,preconditioningandhumidification,gasintroduction,exposure,evacuation,andairwashes)andtakes ...

ETO is absorbed by many materials. For this reason, following sterilization the item must undergo aeration to remove residual ETO. Guidelines have been promulgated regarding allowable ETO limits for devices that depend on how the device is used, how often, and how long in order to pose a minimal risk to patients in normal product use.814

ETO toxicity has been established in a variety of animals. Exposure to ETO can cause eye pain, sore throat, difficulty breathing and blurred vision. Exposure can also cause dizziness, nausea, headache, convulsions, blisters and vomiting and coughing.873 In a variety of in vitro and animal studies, ETO has been demonstrated to be carcinogenic. ETO has been linked to spontaneous abortion, genetic damage, nerve damage, peripheral paralysis, muscle weakness, and impaired thinking and memory.873 Occupational exposure in healthcare facilities has been ...