The invasive assessment of coronary atherosclerosis and ... | 合法醫療器材資訊網

由MAulHaq著作·2013·被引用8次—OCTisaninvasiveimagingmethodperformedinconjunctionwithcoronaryangiography.Thepatientispreparedinthestandardsterilefashionwithasheath​ ...

Atherosclerotic plaque in the coronary tree may manifest as either an acute coronary syndrome (ACS) or stable angina pectoris. An ACS is long thought to be triggered by the rupture of vulnerable atherosclerotic plaque.1 ,2 The hallmark of the so-called ‘vulnerable plaque’ is a thin-cap fibroatheroma (TCFA) with macrophage infiltration surrounding a lipid-rich necrotic core.3–6[1] This is in contrast to patients with stable angina pectoris who may have coronary flow-limiting vulnerable plaque without acute plaque rupture.7 Autopsy studies suggest that it is the rupture of these vulnerable plaques with TCFA that cause coronary events. Hence, identification and more aggressive management of these patients may prevent future coronary events. Imaging of the coronary arteries has facilitated localisation and treatment of acute thrombi and atherosclerotic plaques thereby providing greater ins...