Xpert GBS Assay for Rapid Detection of Group B ... | 合法醫療器材資訊網

由CJost著作·2014·被引用12次—TheXpertGBSassay(Cepheid)isamarketedreal-timePCRforscreeningmaternalcarriagebydetectingGBSDNAinvaginalorrectalspecimens.Recently,two ...

The Xpert GBS real-time PCR assay was applied to gastric fluid samples from 143 newborns, and it detected group B streptococcus (GBS) within 1 h for 16 (11.2%) cases, while microscopic examination detected only 2 cases. The sensitivity and specificity of the Xpert GBS were 80% and 100%, respectively, with regard to 20 cases of GBS colonization or infection. Concordance of Xpert GBS results versus culture was 92.3%. This test detects in a timely manner newborns at risk for invasive GBS disease.

Early-onset group B streptococcus (GBS) neonatal disease is a serious and frequent complication of birth in developed countries. GBS causes more than one-third of the materno-fetal infections (MFI) of term infants, followed by Escherichia coli and other Streptococcus spp., as well as species now classified in the Enter...