Why is leukocyte reduction needed? | 合法醫療器材資訊網
![Why is leukocyte reduction needed?](https://i.imgur.com/6y29Lx7.jpg)
Methodsofleukocytereductionincludecentrifugation,washing,freezing,buffycoatremovalandfiltration.Efficiencyvariesineachmethod.Sepacellfiltersapply ...
![Why is leukocyte reduction needed?](https://i.imgur.com/6y29Lx7.jpg)
It was discovered in the 1950s that leukocytes present in blood sensitize transfusion recipients, resulting in Nonhemolytic FebrileTransfusion Reaction (NHFTR). Since then, allogeneic leukocytes in various blood components have been shown to be involved in a number of adverse responses in recipients.
The following table shows the relationship between the number of residual leukocytes and adverse reactions. Side effects can be avoided if residual leukocytes are reduced to around 106, which most researchers currently agree is the target.
Methods of leukocyte reduction include centrifugation, washing, freezing, buffy coat removal and filtration. Efficiency varies in each method.
Sepacell filters apply selective filtration technol...
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Why is leukocyte reduction needed? | 合法醫療器材資訊網
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