载脂蛋白A1 | 合法醫療器材資訊網

載脂蛋白A1（英語：ApolipoproteinA1，簡稱ApoA1）為附著於高密度脂蛋白（​HDL）及乳靡小球上的載脂蛋白，基因編碼為「APOA1」。...研究指出，APOA1​的 ...

As a major component of the high-density lipoprotein complex (protective "fat removal" particles), apo A1 helps to clear fats, including cholesterol, from white blood cells within artery walls, making the WBCs less likely to become fat overloaded, transform into foam cells, die and contribute to progressive atheroma. Five of nine men found to carry a mutation (E164X) who were at least 35 years of age had developed premature coronary artery disease.[10]One of four mutants of apo A1 is present in roughly 0.3% of the Japanese population, but is found in 6% of those with low HDL cholesterol levels.

ApoA-1 Milano is a naturally occurring mutant of apo A1, found in a few families in Limone sul Garda, Italy, and, by genetic + church record family tree detective work, traced to a single individual in the 14th century. D...