Autoimmunity | 合法醫療器材資訊網

TheLIAISON®dsDNAassayuseschemiluminescentimmunoassay(CLIA)technologyforthequantitativedeterminationofautoantibodiesofIgGclassdirected ...

The LIAISON® ANA Screen assay uses chemiluminescent immunoassay (CLIA) technology for the collective qualitative determination of autoantibodies directed against the following antigens: double-stranded DNA (dsDNA), RNP/Sm (70 kDa), SSA (Ro) (rich in 60 kDa), SS-B (La), Scl-70, Jo-1, centromere (CENP-B) and mitochondria in human serum or plasma, along with detection of sera positive for HEp-2 immunofluorescence antibody test. This test is intended as an aid in the diagnosis of connective tissue diseases (CTD), such as systemic lupus erythematosus (SLE), mixed connective tissue disease (MCTD), Sjögrens syndrome (SS), systemic sclerosis (Ssc), idiopatic polymyositis (PM), dermatomyositis (DM) and CREST syndrome (calcinosis, Raynaud phenomenon, esophageal dysmotility, sclerodactyly and telangiectasia). The test has to be performed on the LIAISON® Analyzer.