Basal ganglia outputs map instantaneous position coordinates ... | 合法醫療器材資訊網

由JWBarter著作·2015·被引用66次—...gangliaoutputsmapinstantaneouspositioncoordinatesduringbehavior.JNeurosci.2015Feb11;35(6):2703-16.doi:10.1523/JNEUROSCI.3245-14.2015.

Figure 14.

Hypothetical BG circuit. SNr neurons receive projections from the striatum and external globus…

Hypothetical BG circuit. SNr neurons receive projections from the striatum and external globus pallidus, via the direct (D, striatonigral) and indirect (I, striatopallidal) pathways. Although these projections are GABAergic, the net effect on the SNr can be either inhibitory (−) or excitatory (disinhibitory, +). Both types of signals, corresponding to a velocity error signal from the striatum, enter the SNr integrator, which is assumed to be leaky. Of course, direct and indirect pathways are not the only possible neural implementation of the proposed circuit. The key component is a phase splitter that generates opponent position reference signals from the SNr to the relevant downstream position controllers. Similar to reciprocal inhibition in the spinal cor...